Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Runx1  runt related transcription factor 1   (Synonyms: AML1, Cbfa2, Pebp2a2, runt domain, alpha subunit 2)
Results	Reference
1*	J:93240 Brenner O, Levanon D, Negreanu V, Golubkov O, Fainaru O, Woolf E, Groner Y, Loss of Runx3 function in leukocytes is associated with spontaneously developed colitis and gastric mucosal hyperplasia. Proc Natl Acad Sci U S A. 2004 Dec 9;101(45):16016-21
1	J:326957 Cao Z, Huang C, Lu F, Jiang X, Hu Y, Cao C, Liu Z, Meis1 Regulates Nociceptor Development and Behavioral Response to Tactile Stimuli. Front Mol Neurosci. 2022;15:901466
1	J:106971 Chen CL, Broom DC, Liu Y, de Nooij JC, Li Z, Cen C, Samad OA, Jessell TM, Woolf CJ, Ma Q, Runx1 determines nociceptive sensory neuron phenotype and is required for thermal and neuropathic pain. Neuron. 2006 Feb 2;49(3):365-77
1*	J:254788 Chen Z, Donnelly CR, Dominguez B, Harada Y, Lin W, Halim AS, Bengoechea TG, Pierchala BA, Lee KF, p75 Is Required for the Establishment of Postnatal Sensory Neuron Diversity by Potentiating Ret Signaling. Cell Rep. 2017 Oct 17;21(3):707-720
1	J:283226 Desiderio S, Vermeiren S, Van Campenhout C, Kricha S, Malki E, Richts S, Fletcher EV, Vanwelden T, Schmidt BZ, Henningfeld KA, Pieler T, Woods CG, Nagy V, Verfaillie C, Bellefroid EJ, Prdm12 Directs Nociceptive Sensory Neuron Development by Regulating the Expression of the NGF Receptor TrkA. Cell Rep. 2019 Mar 26;26(13):3522-3536.e5
1	J:160718 Dykes IM, Lanier J, Eng SR, Turner EE, Brn3a regulates neuronal subtype specification in the trigeminal ganglion by promoting Runx expression during sensory differentiation. Neural Dev. 2010;5:3
1	J:164668 Gascon E, Gaillard S, Malapert P, Liu Y, Rodat-Despoix L, Samokhvalov IM, Delmas P, Helmbacher F, Maina F, Moqrich A, Hepatocyte growth factor-Met signaling is required for Runx1 extinction and peptidergic differentiation in primary nociceptive neurons. J Neurosci. 2010 Sep 15;30(37):12414-23
1	J:345606 Gonzalez Galofre ZN, Kilpatrick AM, Marques M, Sa da Bandeira D, Ventura T, Gomez Salazar M, Bouilleau L, Marc Y, Barbosa AB, Rossi F, Beltran M, van de Werken HJG, van IJcken WFJ, Henderson NC, Forbes SJ, Crisan M, Runx1+ vascular smooth muscle cells are essential for hematopoietic stem and progenitor cell development in vivo. Nat Commun. 2024 Feb 23;15(1):1653
1	J:210892 Gorokhova S, Gaillard S, Urien L, Malapert P, Legha W, Baronian G, Desvignes JP, Alonso S, Moqrich A, Uncoupling of molecular maturation from peripheral target innervation in nociceptors expressing a chimeric TrkA/TrkC receptor. PLoS Genet. 2014 Feb;10(2):e1004081
1	J:204192 Hadjab S, Franck MC, Wang Y, Sterzenbach U, Sharma A, Ernfors P, Lallemend F, A local source of FGF initiates development of the unmyelinated lineage of sensory neurons. J Neurosci. 2013 Nov 6;33(45):17656-66
1	J:320355 Li H, Zhao X, Yan X, Jessen WJ, Kim MO, Dombi E, Liu PP, Huang G, Wu J, Runx1 contributes to neurofibromatosis type 1 neurofibroma formation. Oncogene. 2016 Mar 17;35(11):1468-74
1*	J:186470 Lopes C, Liu Z, Xu Y, Ma Q, Tlx3 and runx1 act in combination to coordinate the development of a cohort of nociceptors, thermoceptors, and pruriceptors. J Neurosci. 2012 Jul 11;32(28):9706-15
1	J:298674 Mevel R, Steiner I, Mason S, Galbraith LC, Patel R, Fadlullah MZ, Ahmad I, Leung HY, Oliveira P, Blyth K, Baena E, Lacaud G, RUNX1 marks a luminal castration-resistant lineage established at the onset of prostate development. Elife. 2020 Oct 7;9:e60225
1	J:211575 Murthy M, Bocking S, Verginelli F, Stifani S, Transcription factor Runx1 inhibits proliferation and promotes developmental maturation in a selected population of inner olfactory nerve layer olfactory ensheathing cells. Gene. 2014 May 1;540(2):191-200
1	J:171374 Osorio KM, Lilja KC, Tumbar T, Runx1 modulates adult hair follicle stem cell emergence and maintenance from distinct embryonic skin compartments. J Cell Biol. 2011 Apr 4;193(1):235-50
1	J:125830 Pozner A, Lotem J, Xiao C, Goldenberg D, Brenner O, Negreanu V, Levanon D, Groner Y, Developmentally regulated promoter-switch transcriptionally controls Runx1 function during embryonic hematopoiesis. BMC Dev Biol. 2007;7:84
1	J:242690 Qi L, Huang C, Wu X, Tao Y, Yan J, Shi T, Cao C, Han L, Qiu M, Ma Q, Liu Z, Liu Y, Hierarchical Specification of Pruriceptors by Runt-Domain Transcription Factor Runx1. J Neurosci. 2017 May 31;37(22):5549-5561
1	J:116050 Raveh E, Cohen S, Levanon D, Negreanu V, Groner Y, Gat U, Dynamic expression of Runx1 in skin affects hair structure. Mech Dev. 2006 Nov;123(11):842-50
1	J:235958 Rousso DL, Qiao M, Kagan RD, Yamagata M, Palmiter RD, Sanes JR, Two Pairs of ON and OFF Retinal Ganglion Cells Are Defined by Intersectional Patterns of Transcription Factor Expression. Cell Rep. 2016 May 31;15(9):1930-44
1	J:264483 Tang X, Sun L, Jin X, Chen Y, Zhu H, Liang Y, Wu Q, Han X, Liang J, Liu X, Liang Z, Wang G, Luo F, Runt-Related Transcription Factor 1 Regulates LPS-Induced Acute Lung Injury via NF-kappaB Signaling. Am J Respir Cell Mol Biol. 2017 Aug;57(2):174-183
1	J:228807 Umansky KB, Gruenbaum-Cohen Y, Tsoory M, Feldmesser E, Goldenberg D, Brenner O, Groner Y, Runx1 Transcription Factor Is Required for Myoblasts Proliferation during Muscle Regeneration. PLoS Genet. 2015 Aug;11(8):e1005457
1	J:187723 Zusso M, Methot L, Lo R, Greenhalgh AD, David S, Stifani S, Regulation of postnatal forebrain amoeboid microglial cell proliferation and development by the transcription factor runx1. J Neurosci. 2012 Aug 15;32(33):11285-98